Hypersplenism in Wilson's disease

Anesthetic Management of a Pediatric Patient With Wilsons Disease

UNLABELLED Wilsons disease, characterized by cirrhosis, extrapyramidal symptoms and Kayser-Fleischer corneal rings, is a rare hereditary disease of human copper metabolism. Clinical findings in Wilsons disease are complex and neurological symptoms such as tremor, dysarthria, rigid dystonia, seizures, psychiatric disorders, acute liver failure, chronic hepatitis or cirrhosis may develop. A 4-yea...

Hypersplenism in cirrhosis.

Copper storage diseases: Menkes, Wilsons, and cancer.

The trace element copper is vital to the healthy functioning of organisms. Copper is used in a multitude of cellular activities including respiration, angiogenesis, and immune responses. Like other metals, copper homeostasis is a tightly regulated process. Copper is transported from dietary intake through the serum and into cells via a variety of transporters. There are a variety of copper chap...

Hypersplenism: History and current status

Hypersplenism is a common disorder characterized by an enlarged spleen which causes rapid and premature destruction of blood cells. This review summarizes the history of hypersplenism, discuss its classification and pathogenesis, and examines its diagnosis and treatment options. We performed a comprehensive literature search using PubMed, Web of Knowledge and the China National Knowledge Infras...

Humoral factor (s) in experimental hypersplenism.

I HE SYNDROME of hypersplenism is characterized by splenomegaly, selective or total blood cytopenias, normal or hyperplastic bone marrow, and disappearance of the cytopenias after splenectomy. The mechanism of the various forms of hypersplenism ( splenic thrombocytopenia, spenic anemia, splenic neutropenia, splenic pancytopenia ) is still under discussion. Clinical and experimental evidence has...